Hostal Persal is built in a building dating to 1871 which preserves its original structure, and has 80 bedrooms. It is located in the Barrio de las Letras, in the very heart of the historical and tourist centre of Madrid. 100 metres from Puerta del Sol, beside Plaza de Santa Ana and very close to Plaza Mayor and Prado, Thyssen and Reina Sofa museums..
Hostal Persal is located in a pedestrianised area with access for taxis and private vehicles to its doorstep. There are two public car parks just 50 metres from hostal (Plaza Santa Ana and Plaza Jacinto Benavente). Plaza de Santa Ana is famous for being an area for tapas and nightlife.